Survival after in-hospital pediatric cardiac arrest is only about 40%, and less than 10% for out-of-hospital pediatric cardiac arrest. Thus, prevention of cardiac arrest is of paramount importance. This program reviews the clinical signs and symptoms of shock and respiratory failure – the two most common pathways by which children progress to cardiorespiratory failure and cardiac arrest – and describes how early recognition and intervention can help prevent these events and improve patient outcomes. The course is intended for physicians and nurses who are responsible for the care of sick infants and children.