Infectious Complications in the Hematopoietic Stem Cell Transplant Patient
Learning Objectives
Describe patterns of immune reconstitution following hematopoietic stem cell transplantation and how they determine infection risk over time
Identify transplant‑related, patient‑specific, and post‑transplant factors that increase susceptibility to severe infections in HSCT patients
Explain the impact of graft‑versus‑host disease and its treatments on infectious risk in critically ill transplant recipients
Apply a structured, high‑risk approach to the evaluation and initial management of fever in HSCT patients in the ICU setting
Evaluate common bacterial, viral, and fungal infections after HSCT to guide early antimicrobial, antiviral, and antifungal therapy
Author(s)
Leslie Lehmann, MD
Director, Clinical Stem Cell Transplantation Program | Boston Children's Hospital
Medical Director, International Hematology/Oncology/BMT | Boston Children's Hospital
Associate Professor | Harvard Medical School
Aleksandra E. Olszewski, MD
Physician, Assistant Professor of Critical Care Medicine and Pediatrics, Department of Critical Care Medicine | UPMC Children's Hospital of Pittsburgh
Lisa DelSignore, MD
Associate Professor, Fellowship Program Director, Pediatric Critical Care Medicine | Yale University
Traci Wolbrink, MD, MPH
Co-Director, OPENPediatrics; Co-Director, Center for Educational Excellence and Innovation; Program Director, Pediatric Critical Care Medicine Fellowship; Senior Associate in Critical Care Medicine | Boston Children’s Hospital
Associate Professor of Anaesthesia | Harvard Medical School
Citation
Lehmann L, Wolbrink TA, Olszewski A, DelSignore L. Infectious Complications in the Hematopoietic Stem Cell Transplant Patient. 1/2017. Online Video. OPENPediatrics. https://learn.openpediatrics.org/learn/course/internal/view/elearning/3234/infectious-complications-in-the-hematopoietic-stem-cell-transplant-patient.